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Editors' Choice

John F. Foley
6 April 2010: ec102.
Planar cell polarity signaling and fluid flow regulate the orientation of cilia. Abstract »  
Kristen L. Mueller
6 April 2010: ec103.
Cytomegalovirus monkeys can reinfect an already-infected host by evading the CD8+ T cell–mediated immune response. Abstract »  
Laura M. Zahn
6 April 2010: ec104.
Transcriptionally different expression occurs between infected maize tissues and the corn smut infecting these tissues. Abstract »  
Valda Vinson
6 April 2010: ec105.
An occluded site stabilizes charged amino acids as they cross the membrane field to achieve a switchlike channel opening. Abstract »  
Pamela J. Hines
6 April 2010: ec106.
The master transcription factor APETALA1 dynamically regulates a complex genetic network to guide flower development. Abstract »  
L. Bryan Ray
6 April 2010: ec107.
Specific sites within the nucleus may promote maintenance of genes in a state of enhanced responsiveness. Abstract »  

 

Research Articles

Yun He, Haifeng Zhang, Luyang Yu, Murat Gunel, Titus J. Boggon, Hong Chen, and Wang Min
6 April 2010: ra26.
CCM3, which is associated with inherited cerebrovascular defects, prevents ligand-mediated degradation of a receptor involved in blood vessel formation. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Natsuko Izumi, Akio Yamashita, Akihiro Iwamatsu, Rie Kurata, Hiroki Nakamura, Bonnie Saari, Hisashi Hirano, Philip Anderson, and Shigeo Ohno
6 April 2010: ra27.
Two ATPases regulate molecular complexes that ensure genome integrity and accurate gene expression. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Julien A. Sebag and Patricia M. Hinkle
6 April 2010: ra28.
Two homologous accessory proteins exert opposing effects on the responsiveness of the melanocortin 2 receptor to the hormone ACTH. Editor's Summary »   Abstract »   Full Text »   PDF »  

 

Perspectives

Yi Hu and Youren Tong
6 April 2010: pe13.
Inhibition of the kinase activity of LRRK2 may be neuroprotective. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882