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Cover Figure

ONLINE COVER This week's issue features a Research Article describing the mechanisms by which CCM3, which is associated with inherited cerebrovascular defects, regulates vascular development. The image depicts the vasculature of a yolk sac containing a normal mouse embryo. [Image: Yun He, Yale University]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882