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Editors' Choice

Nancy R. Gough
15 June 2010: ec178.
Mated fruit flies eat more protein in response to a peptide in male fly seminal fluid. Abstract »  
John F. Foley
15 June 2010: ec179.
The macrophage-derived protein AIM is taken up by adipocytes and induces a reduction in adipose tissue mass. Abstract »  
Elizabeth M. Adler
15 June 2010: ec180.
Nocturnin promotes the nuclear translocation of PPAR-{gamma}2 and thereby adipogenesis. Abstract »  
Wei Wong
15 June 2010: ec181.
Forced clustering of metabotropic glutamate receptors by β-amyloid oligomers causes increased calcium influx. Abstract »  
Nancy R. Gough
15 June 2010: ec182.
Platelet aggregation is kept in check by inhibitory signaling from protein kinase A released from the IKK (inhibitor of nuclear factor {kappa}B kinase) complex. Abstract »  
Pamela J. Hines
15 June 2010: ec183.
To prevent too much myelin from causing trouble, two proteins act to limit insulation of axons. Abstract »  
L. Bryan Ray
15 June 2010: ec184.
Modeling and experiments help explain responsiveness of red blood cell precursors to very large changes in a proliferative signal. Abstract »  


Research Articles

Hauke Cornils, Mario R. Stegert, Alexander Hergovich, Debby Hynx, Debora Schmitz, Stephan Dirnhofer, and Brian A. Hemmings
15 June 2010: ra47.
The kinase NDR1 functions as a haploinsufficient tumor suppressor by ensuring proper apoptotic responses. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Sven Kroening and Margarete Goppelt-Struebe
15 June 2010: pl1.
Removable plastic barriers allow quantification of cell migration without damaging either the surface proteins or the cells. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882