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Editors' Choice

John F. Foley
22 June 2010: ec185.
Competition between nitrate and auxin for binding to the nitrate transporter protein NRT1.1 regulates the growth of lateral roots in plants. Abstract »  
Annalisa M. VanHook
22 June 2010: ec186.
A glycosome-associated switch regulates transition of trypanosomes from host- to vector-specific forms. Abstract »  
Nancy R. Gough
22 June 2010: ec187.
Following spinal cord injury, motoneurons switch to a constitutively active serotonin receptor, which contributes to muscle spasticity. Abstract »  
Elizabeth M. Adler
22 June 2010: ec188.
Modulation of 5-HT1A receptor–associated G{alpha}i2 activity has antidepressant-like effects in mice. Abstract »  
Paula A. Kiberstis
22 June 2010: ec189.
A small noncoding RNA helps regulate cholesterol levels in mice. Abstract »  
Guy Riddihough
22 June 2010: ec190.
A viral noncoding RNA regulates the level of a complementary host cell’s microRNA. Abstract »  


Editorial Guides

Rune Linding
22 June 2010: eg4.
Understanding the implications of the changes in signaling systems requires analysis in both cellular and evolutionary time scales. Abstract »   Full Text »   PDF »   Evolution Series I »  


Research Articles

Øyvind Dahle, Amit Kumar, and Michael R. Kuehn
22 June 2010: ra48.
Developmental signaling integrates with epigenetic processes to control the expression of Nodal target genes. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Edward M. De Robertis
22 June 2010: pe21.
Positional information generated by Wnt signaling determines whether heads or tails will form in wounded flatworms. Abstract »   Full Text »   PDF »  
Vincent C. Panzano, Kyeongjin Kang, and Paul A. Garrity
22 June 2010: pe22.
Many vertebrates and invertebrates rely on the ion channel TRPA1 to detect both warmth and chemicals. Abstract »   Full Text »   PDF »  
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