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ONLINE COVER This week features a Research Article describing a mathematical model that explains how errors are minimized in the specification of cells that form sensory bristles on flies. The analysis revealed that accurate selection of bristle-forming sensory organ precursor cells in fruit flies requires cell-autonomous Notch-ligand interactions to prevent inappropriate fate specification in neighboring cells. The cover image shows a fly with extra bristles due to an error in the fate specification of the sensory organ precursor cells. [Image: Omer Barad, Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882