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Cover Figure

ONLINE COVER This week's issue features a Research Article that describes the contributions of individual phosphatidylinositol 3-kinase (PI3K) isoforms to antigen-dependent and antigen-independent B cell receptor signaling. The image shows CD4+ T cells (blue) and two types of B cells (red and green) in the mouse spleen, the site of B cell development. [Image: Fabien Garcon, Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, UK]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882