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Editors' Choice

Annalisa M. VanHook
31 August 2010: ec262.
Focal adhesion kinase is required for intestinal tumorigenesis and regeneration but dispensable for homeostasis. Abstract »  
Nancy R. Gough
31 August 2010: ec263.
By inhibiting the production of a microRNA, the deacetylase SIRT1 and the transcriptional repressor YY1 allow memory formation. Abstract »  
Wei Wong
31 August 2010: ec264.
The insecticide DEET activates gustatory receptors to induce aversive responses in Drosophila. Abstract »  
Laura M. Zahn
31 August 2010: ec265.
Damage caused by a caterpillar releases compounds that are transformed by the pest’s saliva into a predator attractant. Abstract »  
John F. Foley
31 August 2010: ec266.
The Drosophila PP2A phosphatase complex dSTRIPAK dephosphorylates Hippo to inhibit Hippo signaling. Abstract »  
Pamela J. Hines
31 August 2010: ec267.
Short-range signaling by sulfated peptides maintains root stem cells. Abstract »  
Stella M. Hurtley
31 August 2010: ec268.
Lipid signaling in yeast is regulated by intracellular pH. Abstract »  
Pamela J. Hines
31 August 2010: ec269.
Muscle stem cells prefer a soft substrate. Abstract »  


Editorial Guides

Nancy R. Gough and John F. Foley
31 August 2010: eg6.
Kinases and phosphatases are stars in the signaling universe. Abstract »   Full Text »   PDF »  



Benoit Boivin, Ming Yang, and Nicholas K. Tonks
31 August 2010: pl2.
Mildly acidic pH and degassed buffers are the keys to successfully identifying redox-sensitive tyrosine phosphatases. Abstract »   Full Text »   PDF »  


Research Resources

Yutaka Arimura and Junji Yagi
31 August 2010: rs1.
Gene expression analysis suggests that protein tyrosine phosphatases exhibit immune cell–specific expression profiles. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Daniel Schwartz and George M. Church
31 August 2010: rs2.
A database of known phosphorylation sites on viral proteins also enables the prediction of other potential sites. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882