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Editors' Choice

John F. Foley
12 October 2010: ec312.
Ketone bodies compete with chloride ions for binding to vesicular glutamate transporters, thus inhibiting glutamate release. Abstract »  
Annalisa M. VanHook
12 October 2010: ec313.
Abl tyrosine kinases phosphorylate Dsh to influence planar cell polarity without affecting canonical Wnt signaling. Abstract »  
Nancy R. Gough
12 October 2010: ec314.
AUXIN BINDING PROTEIN 1 mediates rapid auxin responses in roots and leaves. Abstract »  
L. Bryan Ray
12 October 2010: ec315.
Individual control of amplitude, frequency, and damping of a biological oscillator is demonstrated in cultured cells. Abstract »  
Guy Riddihough
12 October 2010: ec316.
A critical regulator of cell division is recruited to chromosomes through the specific phosphorylation of a chromatin protein. Abstract »  
Paula A. Kiberstis
12 October 2010: ec317.
Genetic analysis of a rare but aggressive form of ovarian cancer implicates a chromatin remodeling defect in disease development. Abstract »  


Editorial Guides

Nancy R. Gough
12 October 2010: eg9.
Understanding the molecular details of the response to endocrine hormones should improve treatment options and approaches. Abstract »   Full Text »   PDF »  


Research Articles

Danielle Duma, Jennifer B. Collins, Jeff W. Chou, and John A. Cidlowski
12 October 2010: ra74.
Glucocorticoids are more effective at counteracting inflammation in males than in females. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



George P. Chrousos
12 October 2010: pe36.
Males and females show different responses to stress and to the anti-inflammatory actions of glucocorticoids. Abstract »   Full Text »   PDF »  



Ana Claudia Latronico and Ze’ev Hochberg
12 October 2010: re7.
Mutations in GPCRs are associated with several disorders that affect the development and maturation of children and adolescents. Gloss »   Abstract »   Full Text »   PDF »  


Meeting Reports

Li Chan, Kerstin Albertsson-Wikland, Cecilia Camacho-Hübner, and Ze'ev Hochberg
12 October 2010: mr3.
The New Inroads to Child Health Conference focused on plasma membrane receptor-mediated pathways involved in endocrine signaling. Abstract »   Full Text »   PDF »  



Ze'ev Hochberg
12 October 2010: pt1.
Molecular defects at various steps in hormone production, signaling, or responsiveness can cause disease. Abstract »   Full Text »   PDF »   Slideshow »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882