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ONLINE COVER This week features a Perspective that describes nonnuclear functions for transcription factors in platelets, which lack nuclei and play a key role in blood clotting. The image shows an artist's representation of platelets ensnared in a mesh of extracellular matrix proteins. [Image: Yana Hammond, Science Signaling]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882