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Cover Figure

ONLINE COVER This week, Science Signaling publishes a Focus Issue that complements the Science Special Issue on Epigenetics. Highlights include signaling pathways that alter epigenetic patterning, transcriptional network organization, and posttranscriptional regulation of signaling molecules by microRNAs. The image depicts a section of normal human colon stained for DNMT1, one of the key enzymes that maintains DNA methylation patterns. [Credit: Yiqing Zhao, Department of Genetics and Case Comprehensive Cancer Center, Case Western Reserve University]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882