ONLINE COVER This week, Science Signaling publishes a Focus Issue that complements the Science Special Issue on Glia. Highlights include a Research Article by Fan et al. on mechanisms by which glial-derived brain cancer resists drugs, a Perspective by Ballanyi et al. on how astrocytes participate in regulating breathing, and a Teaching Resource by and Podcast interview with R. D. Fields. The image shows glial cells (green and red) and neurons (blue) from a rat hippocampal culture. [Image: Jonathan Cohen, Nervous Systems Development and Plasticity Section, National Institute of Child Health and Human Development, National Institutes of Health]

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