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Editors' Choice

Wei Wong
23 November 2010: ec354.
Gradients of reactive oxygen species determine whether cells proliferate or differentiate in Arabidopsis roots. Abstract »  
Elizabeth M. Adler
23 November 2010: ec355.
COI1, JAZ, and inositol pentakisphosphate act as a three-molecule jasmonate co-receptor complex. Abstract »  
Annalisa M. VanHook
23 November 2010: ec356.
Different Wnt ligands use a common mechanism to activate unrelated receptors to initiate canonical or noncanonical Wnt signaling. Abstract »  
L. Bryan Ray
23 November 2010: ec357.
Epinephrine and norepinephrine produce distinct conformational changes in their receptor and distinct signaling output. Abstract »  
Valda Vinson
23 November 2010: ec358.
Discovery of a binding site in the extracellular domain of a dopamine receptor offers hope for more selective therapeutics. Abstract »  
Valda Vinson
23 November 2010: ec359.
Five crystal structures provide insight into chemokine and HIV-1 recognition. Abstract »  
Kristen L. Mueller
23 November 2010: ec360.
A protein that inhibits apoptosis is essential for the survival of immune memory cells. Abstract »  
Peter R. Stern
23 November 2010: ec361.
The subunit composition of AMPA receptors at lateral amygdala synapses changes after the acquisition of associative fear. Abstract »  



Elaine F. Reed and Annalisa M. VanHook
23 November 2010: pc21.
Targeting interactions between HLA-I and the integrin β4 subunit is a potential strategy for preventing transplant rejection. Abstract »   Full Text »   Podcast »  


Research Articles

Ryan B. Corcoran, Dora Dias-Santagata, Kristin Bergethon, A. John Iafrate, Jeffrey Settleman, and Jeffrey A. Engelman
23 November 2010: ra84.
Amplification of an upstream gene leads to resistance to cancer drugs targeted downstream. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Xiaohai Zhang, Enrique Rozengurt, and Elaine F. Reed
23 November 2010: ra85.
Interactions between human leukocyte antigen I and the integrin β4 subunit may contribute to transplant rejection. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Regine Hengge
23 November 2010: pe44.
A bacterial second messenger regulates mRNA translation by altering the cleavage of a self-splicing intron. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882