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Cover Figure

ONLINE COVER This week features a Perspective that describes how a ubiquitous bacterial signaling molecule regulates the splicing of an mRNA for a putative virulence gene in Clostridium difficile. The image shows the structure of cyclic-di-GMP. [Image: Yana Hammond, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882