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Cover Figure

ONLINE COVER This week features a Perspective that discusses the compartment-specific control of signaling through the Toll-like receptor 9 (TLR9), which senses foreign DNA. The image shows the endosomal compartments in which TLR9 can be activated. [Image: Yana Hammond, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882