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ONLINE COVER This week's issue features a Research Article that describes a model for the migration of cells in a chemotactic gradient. In particular, the model describes how cells can exhibit migration either in a straight line or in an alternating left-right pattern, which occurs when the leading edge of a cell forms branched protrusions, only one of which persists. The image shows the results from a simulation of the leading edge of a migrating cell, with areas of membrane retraction (blue) and branched protrusions (red). [Image: Mikiya Otsuji, University of Tokyo, Japan] |
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882