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Cover Figure

ONLINE COVER This week the editors celebrate the most exciting and notable advances in the field of cell signaling from 2010. The Editorial Guide highlights research nominated by members of the Editorial Board that spans the "mega"—large-scale systems analyses—and the "micro"—protein structures—along with new findings in metabolism and genetics. Other nominations included studies that may lead to new therapeutic avenues for cancer, diabetes, and Alzheimer's disease. [Image: Duncan Smith/Thinkstock]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882