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Editors' Choice

Wei Wong
11 January 2011: ec10.
A bacterial effector protein acts as an artificial scaffold for a GTPase and kinase at the Golgi. Abstract »  
John F. Foley
11 January 2011: ec11.
Oscillations in the activity of mTOR regulate the responsiveness of regulatory T cells. Abstract »  
Nancy R. Gough
11 January 2011: ec12.
A free-living nematode relies on a receptor guanylate cyclase and a cGMP-gated channel to move away from carbon dioxide. Abstract »  
Pamela J. Hines
11 January 2011: ec13.
Spring flowering enabled by a winter chill is regulated by interplay between protein-coding and noncoding RNA transcripts. Abstract »  
Peter R. Stern
11 January 2011: ec14.
Neuronal gap junction channels containing connexin 36 proteins participate in consolidation of fear memories. Abstract »  


Research Articles

Yun Rose Li and Hiroaki Matsunami
11 January 2011: ra1.
Crosstalk between neurotransmitter signaling and odorant signaling may enhance the sense of smell. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Randy A. Hall
11 January 2011: pe1.
Associations between receptors for odorants and acetylcholine result in enhanced odorant receptor signaling. Abstract »   Full Text »   PDF »  


Meeting Reports

Elizabeth F. Smith and Rajat Rohatgi
11 January 2011: mr1.
Scientists discussed advances in cilia biology and the role of cilia in development and disease. Abstract »   Full Text »   PDF »  


Teaching Resources

R. Douglas Fields
11 January 2011: tr1.
Physical changes associated with the electrical activity of neurons mediate intercellular signaling. Abstract »   Full Text »   PDF »   Movies »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882