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Cover Figure

ONLINE COVER This week features a Research Article that describes a signaling pathway initiated in the endoderm and mesoderm germ layers that promotes survival of the ectoderm. The image shows the excessive numbers of dying (dark blue) cells in the ectoderm of a stage 17 frog embryo in which serum- and glucocorticoid-inducible kinase 1 activity was knocked down. [Image: Tatsuya Endo (Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University)]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882