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Cover Figure

ONLINE COVER This week features a Research Article that suggests that mitochondrial membrane potential is required for immune responses to cellular viruses mediated by the mitochondrial outer membrane adaptor protein MAVS. The image shows mouse embryo fibroblasts stained for MAVS (red) and mitochondrial Hsp70 (green) to identify mitochondria (yellow). [Image: Kai Yasukawa and Takumi Koshiba, Kyushu University, Japan]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882