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Editors' Choice

Wei Wong
22 March 2011: ec82.
JNK signaling promotes the elimination of neoplastic cells in Drosophila epithelia. Abstract »  
John F. Foley
22 March 2011: ec83.
The binding of vitamin A to its uptake receptor activates JAK-STAT signaling and gene expression. Abstract »  
Elizabeth M. Adler
22 March 2011: ec84.
Progesterone stimulates calcium influx in human sperm through the CatSper channel. Abstract »  
Nancy R. Gough
22 March 2011: ec85.
Protein kinase C-{theta} acts directly at gene promoters to participate in inducible gene expression. Abstract »  
Annalisa M. VanHook
22 March 2011: ec86.
Ras-MAPK signaling modulates innate immunity in the fly. Abstract »  
Pamela J. Hines
22 March 2011: ec87.
Neurons in the brain that boost the morning response of the circadian rhythm are themselves directly responsive to light. Abstract »  
Nancy R. Gough
22 March 2011: ec88.
Reducing the abundance of follistatin-like 3, a secreted antagonist of members of the transforming growth factor–β family, reduces cardiac hypertrophy. Abstract »  

 

Research Articles

Ken S. Lau, Alwin M. Juchheim, Kimberly R. Cavaliere, Sarah R. Philips, Douglas A. Lauffenburger, and Kevin M. Haigis
22 March 2011: ra16.
A systems-level analysis of signaling in the mouse intestine identifies critical mediators of inflammation and regionally specific responses. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  

 

Perspectives

Pilar Martín and Francisco Sánchez-Madrid
22 March 2011: pe14.
CD69 deficiency promotes differentiation of inflammatory TH17 cells and exacerbates autoimmune diseases in mice. Abstract »   Full Text »   PDF »  

 

Meeting Reports

Fan Pan, Huimin Fan, Ling Lu, Zhongmin Liu, and Shuiping Jiang
22 March 2011: mr4.
This meeting in Shanghai focused on the relationship between regulatory and inflammatory T cells. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882