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Editors' Choice

Elizabeth M. Adler
26 April 2011: ec114.
Tumor cells transmit endoplasmic reticulum stress to macrophages to promote an inflammatory microenvironment. Abstract »  
Wei Wong
26 April 2011: ec115.
Caspase activity in microglia does not trigger cell death, but rather induces proinflammatory responses. Abstract »  
Pamela J. Hines
26 April 2011: ec116.
Amino acid modulation of Ca2+ signaling guides growth of plant pollen tubes. Abstract »  
Annalisa M. VanHook
26 April 2011: ec117.
Hippo antagonizes Wnt signaling to restrict proliferation of cardiomyocytes, thereby regulating heart size. Abstract »  
John F. Foley
26 April 2011: ec118.
Major histocompatibility class II molecules promote Toll-like receptor signaling in macrophages and dendritic cells. Abstract »  
Kristen L. Mueller
26 April 2011: ec119.
A growth factor protects against arthritis in mice by blocking tumor necrosis factor–dependent signaling. Abstract »  
Pamela J. Hines
26 April 2011: ec120.
One receptor binds two different types of proteoglycan at the same site but with divergent outcomes. Abstract »  
L. Bryan Ray
26 April 2011: ec121.
Cyclin degradation is not the only mechanism that controls the exit of mouse oocytes from meiosis. Abstract »  

 

Editorial Guides

Wei Wong
26 April 2011: eg4.
Various signaling pathways enable cells to sense environmental cues and direct their migration accordingly. Abstract »   Full Text »   PDF »  

 

Journal Club

Adam Byron
26 April 2011: jc3.
The spatial organization of integrin adhesions provides insight into their molecular functions. Abstract »   Full Text »   PDF »  

 

Podcasts

Chuan-ju Liu and Annalisa M. VanHook
26 April 2011: pc8.
A growth factor that antagonizes signaling by tumor necrosis factor–α relieves symptoms of inflammatory arthritis. Abstract »   Full Text »   Podcast »  

 

Research Articles

Akifumi Morinaka, Mayumi Yamada, Rurika Itofusa, Yosuke Funato, Yuta Yoshimura, Fumio Nakamura, Takeshi Yoshimura, Kozo Kaibuchi, Yoshio Goshima, Mikio Hoshino, Hiroyuki Kamiguchi, and Hiroaki Miki
26 April 2011: ra26.
Repulsive guidance signaling triggers the collapse of neuronal growth cones through a mechanism involving oxidation and phosphorylation. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  

 

Perspectives

Philippe V. Afonso and Carole A. Parent
26 April 2011: pe22.
The differentiation or "priming" status of cells may explain contradictory findings for the role of phosphoinositide 3-kinases in chemotaxis. Abstract »   Full Text »   PDF »  
William A. Muller
26 April 2011: pe23.
Neutrophils migrate through inflamed tissue into necrotic tissue by following a restricted set of molecular cues. Abstract »   Full Text »   PDF »  

 

Errata

 
26 April 2011: er2.
The image in the top panel of Fig. 1C was erroneously reversed during processing of the manuscript. Full Text »   PDF »  
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