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Editors' Choice

Annalisa M. VanHook
17 May 2011: ec139.
The hydrolase Notum inhibits Wnt signaling to specify regeneration of head structures in planaria. Abstract »  
Nancy R. Gough
17 May 2011: ec140.
Mosquitoes that feed on warm-blooded animals exhibit a heat shock response in the gut that promotes digestion and fecundity. Abstract »  
John F. Foley
17 May 2011: ec141.
Estrogen receptor β blocks inflammation in a mouse model of multiple sclerosis by transrepressing gene expression. Abstract »  
Nancy R. Gough
17 May 2011: ec142.
Both membrane-bound and cleaved polycystin-1 increase signaling by the transcriptional regulators of the STAT family. Abstract »  
Annalisa M. VanHook
17 May 2011: ec143.
Related transcription factors are differentially regulated by auxin to control development of analogous structures in seed plants and mosses. Abstract »  
Wei Wong
17 May 2011: ec144.
Lipids that bind to mammalian cannabinoid receptors mediate the longevity-promoting effects of dietary restriction in Caenorhabditis elegans. Abstract »  


Research Articles

Kwang-Hyun Park, Byung-Ju Kim, John Kang, Tae-Sik Nam, Jung Min Lim, Hyoung Tae Kim, Jong Kwan Park, Young Gon Kim, Soo-Wan Chae, and Uh-Hyun Kim
17 May 2011: ra31.
Prostate-derived vesicles provide sperm with calcium signaling proteins required for progesterone-induced motility. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Dietmar Geiger, Tobias Maierhofer, Khaled A. S. AL-Rasheid, Sönke Scherzer, Patrick Mumm, Anja Liese, Peter Ache, Christian Wellmann, Irene Marten, Erwin Grill, Tina Romeis, and Rainer Hedrich
17 May 2011: ra32.
Plant survival during periods of drought may involve SLAH3, a nitrate-conducting anion channel activated by abscisic acid. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Dejian Ren
17 May 2011: pe27.
Proteins involved in calcium signaling are delivered to sperm through fusion with prostate-derived vesicles. Abstract »   Full Text »   PDF »  



Illés J. Farkas, Tamás Korcsmáros, István A. Kovács, Ágoston Mihalik, Robin Palotai, Gábor I. Simkó, Kristóf Z. Szalay, Máté Szalay-Beko, Tibor Vellai, Shijun Wang, and Peter Csermely
17 May 2011: pt3.
Analysis of network topology and dynamics holds promise for identifying new sets of potential drug targets. Abstract »   Full Text »   PDF »   Slideshow »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882