24 May 2011
Vol 4, Issue 174

About The Cover

Cover image expansion

Online Cover This week features a Research Article describing how the cell-cell adhesion protein α-catenin suppresses skin carcinoma development by attenuating the signaling of Yap1, a transcriptional coactivator in the Hippo pathway. The image shows a hair follicle from a wild-type mouse stained for α-catenin (green) and a marker of stem and progenitor cells (red). [Image: Bridget T. Kreger, Division of Human Biology, Fred Hutchinson Cancer Research Center]