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Cover Figure

ONLINE COVER This week features a Research Article describing how the cell-cell adhesion protein α-catenin suppresses skin carcinoma development by attenuating the signaling of Yap1, a transcriptional coactivator in the Hippo pathway. The image shows a hair follicle from a wild-type mouse stained for α-catenin (green) and a marker of stem and progenitor cells (red). [Image: Bridget T. Kreger, Division of Human Biology, Fred Hutchinson Cancer Research Center]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882