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Editors' Choice

Nancy R. Gough
31 May 2011: ec151.
A protein in royal jelly, which triggers development of a honeybee queen, is identified and activates the epidermal growth factor receptor pathway. Abstract »  
Annalisa M. VanHook
31 May 2011: ec152.
Opposing signals specify cell fate along the proximal-distal axis of the chick limb. Abstract »  
John F. Foley
31 May 2011: ec153.
Notch signaling regulates sleep in flies and worms. Abstract »  
Nancy R. Gough
31 May 2011: ec154.
The precursor of melatonin is a signaling mediator that stimulates the production of new neurons during sleep. Abstract »  
Nancy R. Gough
31 May 2011: ec155.
Commensal bacteria in the gut stimulate repair of the epithelial barrier by stimulating reactive oxygen species production and cell migration. Abstract »  
Kristen L. Mueller
31 May 2011: ec156.
Human cytomegalovirus uses a host-encoded antiviral protein to its own advantage. Abstract »  


Research Articles

Jeong-Rae Kim, Junil Kim, Yung-Keun Kwon, Hwang-Yeol Lee, Pat Heslop-Harrison, and Kwang-Hyun Cho
31 May 2011: ra35.
An algorithmic approach enables the simplification of complex signaling networks and identifies potential therapeutic targets. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Sven Mesecke, Doris Urlaub, Hauke Busch, Roland Eils, and Carsten Watzl
31 May 2011: ra36.
The extent of phosphorylation of a guanine nucleotide exchange factor determines the cytotoxicity of natural killer cells. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Bingcheng Wang
31 May 2011: pe28.
Eph receptors and their ephrin ligands regulate contact inhibition of locomotion and its evasion in cancer cells. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882