ONLINE COVER This week features a Research Resource reporting a proteomic analysis of SUMOylation in response to inhibition of the proteasome that suggested that the ubiquitin-like protein SUMO participates in the cellular response to stresses that promote accumulation of misfolded proteins. The image shows the structure of human SUMO-1 based on Protein Data Bank ID 1Y8R. [Image: Chris Bickel, AAAS].
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