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ONLINE COVER This week features a Research Article that presents the structure of the light-induced dimer of VIVID, a blue-light sensor and transcriptional regulator found in the filamentous fungus Neurospora crassa. Light-induced conformational changes in one subunit of VIVID facilitate its binding to the other subunit in the dimer. The image shows the ribbon structure of the light-state dimer of VIVID against a backdrop of culture tubes containing Neurospora expressing different variants of VIVID. [Image: A. Vaidya, C.-H. Chen, J. Dunlap, J. Loros, B. Crane, Department of Chemistry and Chemical Biology, Cornell University, and Departments of Genetics and Biochemistry, Dartmouth Medical School]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882