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Cover Figure

ONLINE COVER This week features a Perspective that describes how phosphorylation of the autophagy adaptor optineurin by TBK1, a kinase involved in innate immune responses, limits the growth of a bacterial pathogen. The image shows a Salmonella bacterium in the initial stages of being engulfed by an autophagosome. [Image: Bricelyn Strauch, Science Signaling]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882