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Cover Figure

ONLINE COVER This week features a Research Article that describes how the kinase Itk controls the spatiotemporal patterning of T cell signaling molecules at the interface between the T cell and an antigen-presenting cell (APC) to affect the actin cytoskeleton. The image shows stills from the timed analysis of a fluorescent reporter of a T cell signaling molecule accumulating at the T cell–APC interface. [Image: Kentner Singleton, University of Texas Southwestern Medical Center, USA]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882