ONLINE COVER This week features a Research Article that describes how the kinase Itk controls the spatiotemporal patterning of T cell signaling molecules at the interface between the T cell and an antigen-presenting cell (APC) to affect the actin cytoskeleton. The image shows stills from the timed analysis of a fluorescent reporter of a T cell signaling molecule accumulating at the T cell–APC interface. [Image: Kentner Singleton, University of Texas Southwestern Medical Center, USA]

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