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Editors' Choice

Wei Wong
15 November 2011: ec316.
Acetylation inactivates the transcription factor FoxO1 during nutrient starvation to promote metabolism of lipids over glucose. Abstract »  
John F. Foley
15 November 2011: ec317.
Metabolic processes required for the differentiation of effector T cells are controlled by an orphan nuclear receptor. Abstract »  
Nancy R. Gough
15 November 2011: ec318.
Depletion of cells of phosphatidylcholine activates the transcriptional regulator SREBP-1. Abstract »  
L. Bryan Ray
15 November 2011: ec319.
Inositol pyrophosphates are implicated in coordination of cell proliferation and metabolism. Abstract »  
Kristen L. Mueller
15 November 2011: ec320.
A new tissue-specific pathway for the synthesis of proinflammatory prostaglandins is described. Abstract »  
Kristen L. Mueller
15 November 2011: ec321.
A persisting wave of the cytokine interleukin-6 allows control of chronic viral infections. Abstract »  


Research Articles

Rosetta Merline, Kristin Moreth, Janet Beckmann, Madalina V. Nastase, Jinyang Zeng-Brouwers, José Guilherme Tralhão, Patricia Lemarchand, Josef Pfeilschifter, Roland M. Schaefer, Renato V. Iozzo, and Liliana Schaefer
15 November 2011: ra75.
A component of the extracellular matrix promotes inflammatory responses in sepsis and in tumors. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Shinichi Nakamuta, Yasuhiro Funahashi, Takashi Namba, Nariko Arimura, Marina R. Picciotto, Hiroshi Tokumitsu, Thomas R. Soderling, Akira Sakakibara, Takaki Miyata, Hiroyuki Kamiguchi, and Kozo Kaibuchi
15 November 2011: ra76.
Neurotrophins stimulate calcium signaling to promote axon specification. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Charles Sinclair, Manoj Saini, Ina Schim van der Loeff, Shimon Sakaguchi, and Benedict Seddon
15 November 2011: ra77.
T cell receptor signaling in thymocytes determines their responsiveness to a survival cytokine later in life. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882