ONLINE COVER This week features a Research Article (see also the associated Perspective) describing how signaling through Gαi2 induces hypertrophy and can counterbalance pathways that promote muscle wasting. The image shows sections of tibialis muscle stained for type IIa and IIx myosin heavy chain from mice injected with adenovirus encoding a constitutively active form of Gαi2. [Image: Giulia C. Minetti and Mara Fornaro, Novartis Institutes for Biomedical Research, Basel, Switzerland].
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