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Cover Figure

ONLINE COVER This week features a Focus Issue on Wnt and β-catenin signaling in development and disease. Content in this issue highlights new functions for Wnt in cancer, tooth development, and neuronal pathfinding. The image shows the distribution of Bmp4 in a developing mouse tooth. [Image: Daniel J. O'Connell/Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882