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Editors' Choice

Wei Wong
31 January 2012: ec33.
Exercise triggers release of a myokine from skeletal muscle that induces the "browning" of white adipose tissue. Abstract »  
Nancy R. Gough
31 January 2012: ec34.
The cerebral vasculature responds to reduced oxygen through a pathway involving carbon monoxide and hydrogen sulfide. Abstract »  
Elizabeth M. Adler
31 January 2012: ec35.
Netrin-1 enhances the retention of macrophages and the recruitment of smooth muscle cells, thereby promoting the progression of atherosclerotic lesions. Abstract »  
John F. Foley
31 January 2012: ec36.
C-type lectin receptors activate protein kinase C {delta} in a Syk-dependent manner to stimulate NF-{kappa}B signaling in response to fungi. Abstract »  
Kristen L. Mueller
31 January 2012: ec37.
Antigen distribution across activated B cells influences B-T lymphocyte interactions. Abstract »  
Wei Wong
31 January 2012: ec38.
ATM-mediated phosphorylation of Mdm2 after genotoxic stress causes Mdm2 to promote, rather than inhibit, p53 activity. Abstract »  
Valda Vinson
31 January 2012: ec39.
Structural features provide a basis for understanding gating and ion conduction of these channels. Abstract »  



Caleb M. Cardon, Jared Rutter, and Annalisa M. VanHook
31 January 2012: pc2.
Signaling through PAS kinases bypasses the pro-growth requirement of Tor2 in yeast. Abstract »   Full Text »   Podcast »  


Research Articles

Caleb M. Cardon, Thomas Beck, Michael N. Hall, and Jared Rutter
31 January 2012: ra9.
The Rho1-activating complex formed by yPASK-phosphorylated Ugp1 enables yeast to overcome loss of Tor2 function. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Chun-Lin Chen, Yu Wang, Hiromi Sesaki, and Miho Iijima
31 January 2012: ra10.
A subset of myosin motor proteins binds the membrane phospholipid PIP3 to link membrane and cytoskeletal dynamics. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882