ONLINE COVER This week features a Research Article that shows how ERK and Akt signals are integrated to control cellular proliferation through differential regulation of the cell cycle inhibitor p57. The image shows increased proliferation in response to p57 depletion with shRNA of mammary epithelial cells grown in three-dimensional culture. [Image: Nicole Solimini, Department of Cell Biology, Harvard Medical School, Boston, MA]
Note: The credit was initially incorrectly credited to Tobias Schmelzle. The credit information was updated 7 March 2012.
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882