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ONLINE COVER This week features research that uses bioluminescence resonance energy transfer (BRET) to study conformational changes in β-arrestin (Zimmerman et al.) and Förster resonance energy transfer (FRET) to assess changes in the multiprotein complexes that form during T cell receptor signaling (Pauker et al.). The image is a composite of FRET signals, showing interactions among proteins in response to T cell activation. [Images: Maor H. Pauker, Bar-Ilan University, Ramat-Gan, Israel. Composition: Chris Bickel, AAAS] |
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882