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Cover Figure

ONLINE COVER This week features a Research Article that describes how culturing cardiac precursors on a substratum with a rigidity similar to that of heart tissue increases the yield of endothelial cells, one of the major cell types in the heart. The image shows an artist's depiction of the key role of the GTPase-activating protein p190RhoGAP in sensing substratum rigidity. [Image: Rita Gelin Licht/Johns Hopkins University]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882