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Editors' Choice

Annalisa M. VanHook
17 July 2012: ec188.
A chemokine receptor is required for Hedgehog-stimulated proliferation in endodermal cells. Abstract »  
Ernesto Andrianantoandro
17 July 2012: ec189.
Transient Smad4 nuclear localization governs the dynamics of TGF-β pathway activity. Abstract »  
Nancy R. Gough
17 July 2012: ec190.
Activation of the G protein Gα12 leads to degradation of an inhibitor of mTORC2, which promotes cell migration. Abstract »  
Valda Vinson
17 July 2012: ec191.
A protein-engineering strategy yields a closer look at the receptor-bound water, sodium, and lipid molecules. Abstract »  
Paula A. Kiberstis
17 July 2012: ec192.
Structure-function analyses reveal details of the interaction between two proteins that regulate daily rhythms in mammals. Abstract »  
L. Bryan Ray
17 July 2012: ec193.
The regulation of a yeast cell-growth enzyme is dynamic rather than on-off. Abstract »  

 

Research Articles

Michifumi Yamashita, Saurabh Chattopadhyay, Volker Fensterl, Paramananda Saikia, Jaime L. Wetzel, and Ganes C. Sen
17 July 2012: ra50.
TLR3-mediated antiviral responses require phosphorylation of TLR3 by a growth factor receptor and a nonreceptor tyrosine kinase. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Jing Jin Gu, Catherine P. Lavau, Elena Pugacheva, Erik J. Soderblom, M. Arthur Moseley, and Ann Marie Pendergast
17 July 2012: ra51.
Inhibitors of Abl family kinases block T cell migration and could be used to treat inflammatory diseases. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  

 

Perspectives

Stuart A. Casson and Alistair M. Hetherington
17 July 2012: pe30.
Brassinosteroid signaling is crucial for stomatal development. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882