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Editors' Choice

Annalisa M. VanHook
24 July 2012: ec194.
Local axonal signaling through mTORC1 maintains herpes virus latency in neurons. Abstract »  
Nancy R. Gough
24 July 2012: ec195.
In nerves of the portal vein, antagonism of μ-opioid receptors by peptide products of digestion signals the brain to reduce food intake. Abstract »  
Ernesto Andrianantoandro
24 July 2012: ec196.
SHARP1 mediates ubiquitin-independent targeting of hypoxia-inducible factors to the proteasome, thus reducing breast cancer metastasis. Abstract »  
Pamela J. Hines
24 July 2012: ec197.
Maize anthers use cellular redox status rather than a specific germ cell lineage to signal production of new germ cells. Abstract »  
John F. Foley
24 July 2012: ec198.
The adaptor protein NEMO, which is required for activation of the kinase IKKβ, also controls its specificity to ensure NF-{kappa}B activation. Abstract »  



David G. Kirsch, Chang-Lung Lee, and Annalisa M. VanHook
24 July 2012: pc16.
A transcription factor protects the heart from radiation-induced damage. Abstract »   Full Text »   Podcast »  


Research Articles

Chang-Lung Lee, Everett J. Moding, Kyle C. Cuneo, Yifan Li, Julie M. Sullivan, Lan Mao, Iman Washington, Laura B. Jeffords, Rafaela C. Rodrigues, Yan Ma, Shiva Das, Christopher D. Kontos, Yongbaek Kim, Howard A. Rockman, and David G. Kirsch
24 July 2012: ra52.
Without the transcription factor p53 in cardiac endothelial cells, the heart is more susceptible to radiation-induced damage. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Lakshmi R. Perumalsamy, Nimi Marcel, Sneha Kulkarni, Freddy Radtke, and Apurva Sarin
24 July 2012: ra53.
A cytosolic function of Notch helps regulatory T cells survive. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Lisa M. Minter and Barbara A. Osborne
24 July 2012: pe31.
Cytosolic localization of Notch protects regulatory but not effector T cells from apoptosis caused by cytokine withdrawal. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882