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Cover Figure

ONLINE COVER This week features a Research Article that describes how the heart is more susceptible to radiation-induced damage when the transcription factor p53 is not present in cardiac endothelial cells. In the image, the darker area indicates a necrotic section of myocardium from a mouse with an endothelial cell–specific ablation of p53 that has been irradiated. [Image: Chang-Lung Lee/Duke University Medical Center]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882