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Cover Figure

ONLINE COVER This week features a Research Resource that applied bioinformatics analysis to a BRCT protein-protein interaction network to identify biological processes and protein complexes that integrate the DNA damage response with regulation of the cell cycle. The image shows a network based on the tandem BRCT-mediated protein interactions. The BRCT domain–containing proteins are indicated in yellow. [Image: Chris Bickel/AAAS, adapted from Nicholas Woods and Alvaro Monteiro, Moffitt Cancer Center, Tampa, FL]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882