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Editors' Choice

Ernesto Andrianantoandro
16 October 2012: ec266.
In plants, receptor internalization promotes G protein signaling. Abstract »  
Wei Wong
16 October 2012: ec267.
The Hippo pathway inhibits metastasis of breast cancer cells, a role that is stimulated by the LIF receptor and inhibited by miR-9. Abstract »  
Nancy R. Gough
16 October 2012: ec268.
Cathepsin G secreted from neutrophils cleaves proinflammatory precursors that function as autocrine signals. Abstract »  
Caroline Ash
16 October 2012: ec269.
Cooperating groups of bacteria resist infiltration by noncooperating cheats by co-regulating shared and individual products. Abstract »  
Annalisa M. VanHook
16 October 2012: ec270.
A calcium channel in the nonmotile cilia of crown cells contributes to left-right patterning. Abstract »  
L. Bryan Ray
16 October 2012: ec271.
Light sensing involves contraction of the photoreceptor cell membrane physically gating the light-sensitive channels. Abstract »  


Research Articles

Emeka K. Enwere, Janelle Holbrook, Rim Lejmi-Mrad, Jennifer Vineham, Kristen Timusk, Baktharaman Sivaraj, Methvin Isaac, David Uehling, Rima Al-awar, Eric LaCasse, and Robert G. Korneluk
16 October 2012: ra75.
Muscle fiber formation from progenitor cells is dependent on noncanonical NF-{kappa}B signaling. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Taichiro Tomida, Shigekazu Oda, Mutsuhiro Takekawa, Yuichi Iino, and Haruo Saito
16 October 2012: ra76.
Live-cell imaging in nematodes reveals the complex responses of a mitogen-activated protein kinase to neuronal stimulation. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Edward C. Stites
16 October 2012: pe46.
Targeting the receptor and a mutant component may be an effective colon cancer treatment. Abstract »   Full Text »   PDF »  



David J. Robbins, Dennis Liang Fei, and Natalia A. Riobo
16 October 2012: re6.
The Hedgehog network includes canonical and noncanonical signaling modules important for development, homeostasis, and disease. Gloss »   Abstract »   Full Text »   PDF »  



Achille Gravanis, Theodora Calogeropoulou, Vily Panoutsakopoulou, Kyriaki Thermos, Constantinos Neophytou, and Ioannis Charalampopoulos
16 October 2012: pt8.
Synthetic DHEA analogs promote neuronal survival without estrogenic or androgenic side effects. Abstract »   Full Text »   PDF »   Slideshow »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882