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Cover Figure

ONLINE COVER This week features a Research Article that suggests that the noncanonical NF-κB pathway promotes the fusion of myoblasts into multinuclear myotubes during muscle generation. In mice, loss of cIAP1, an inhibitor of the noncanonical NF-κB pathway, resulted in enhanced fusion of myoblasts compared to that in wild-type mice. The image shows a primary myotube from a mouse deficient in cIAP1, with the myotube stained in red and the nuclei in green. [Image: Emeka Enwere, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Canada]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882