13 November 2012
Vol 5, Issue 250

About The Cover

Cover image expansion

Online Cover This week features a Research Article describing how two single amino acid changes enable the adaptor protein TRAF5 to acquire the TRAF3-like ability to bind to Cardif, a component of a viral response pathway, and thus promote the production of interferon. The image shows the TRAF domain of TRAF3 bound to Cardif. [Image: Chris Bickel/AAAS]