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Cover Figure

ONLINE COVER This week features a Research Article that describes the application of state-space analysis to the p53 network, which identifies a therapeutic strategy for treating cancer. The image shows a simplified p53 network and a representation of an attractor landscape. The valleys in the landscape represent different outcomes, such as cell cycle arrest or apoptosis, to activation of the p53 network. [Image: Kwang-Hyun Cho, Korea Advanced Institute of Science and Technology]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882