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Editors' Choice

Nancy R. Gough
11 December 2012: ec314.
The pathogenic bacterium EHEC relies on fucose produced by a commensal bacterium to regulate its metabolism to maximize effective intestinal colonization. Abstract »  
Guy Riddihough
11 December 2012: ec315.
The complete set of proteins required for a mutagenic DNA-repair pathway is defined in Escherichia coli. Abstract »  
Caroline Ash
11 December 2012: ec316.
Interaction of a platelet protein and a red cell protein enables platelets to attack malarial parasites inside red cells. Abstract »  
Leslie K. Ferrarelli
11 December 2012: ec317.
The transcription factor WRKY15 mediates an organellar switch from salt tolerance to sensitivity. Abstract »  
Wei Wong
11 December 2012: ec318.
Activation of the Hippo pathway suppresses the activity of the mTOR pathway. Abstract »  
L. Bryan Ray
11 December 2012: ec319.
Reducing the rate of phosphorylation of β-catenin leads to an increase in the steady-state level of the unmodified form. Abstract »  
Pamela J. Hines
11 December 2012: ec320.
Androgen-driven changes in receptor expression disrupt a neuronal signaling pathway and deinnervation. Abstract »  
Valda Vinson
11 December 2012: ec321.
The unusual architecture of this ion-channel pore regulates the flow of calcium into cells. Abstract »  
Pamela J. Hines
11 December 2012: ec322.
An inflammatory response to traumatic injury promotes neurogenesis and repair in the zebrafish brain. Abstract »  
John F. Foley
11 December 2012: ec323.
Loss of the histone deacetylase SIRT6 leads to increased glycolysis and tumorigenesis independently of known oncogenes. Abstract »  

 

Letters

Barbara Burtness, Shanthi Marur, Julie E. Bauman, Erica A. Golemis, Ranee Mehra, and Steven J. Cohen
11 December 2012: lc5.
Targeted inhibitors used in cancer treatments may have adverse effects on immune responses. Abstract »   Full Text »   PDF »  

 

Research Articles

Savithri Balasubramanian, Satya Keerthi Kota, Vijay K. Kuchroo, Benjamin D. Humphreys, and Terry B. Strom
11 December 2012: ra90.
The cell surface receptor TIM-1 attenuates kidney cell death after injury in vitro. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Sahana Suresh Babu, Agnieszka Wojtowicz, Marc Freichel, Lutz Birnbaumer, Markus Hecker, and Marco Cattaruzza
11 December 2012: ra91.
Multiple steps drive the stretch-induced nuclear translocation of the mechanotransducer zyxin. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  

 

Meeting Reports

Folkert Verkaar, Ken M. Cadigan, and Renée van Amerongen
11 December 2012: mr2.
Researchers gathered to share the latest findings on Wnt signaling in development and disease. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882