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Cover Figure

ONLINE COVER This week features a Research Article that shows the kinase PI3Kγ promotes cardiac hypertrophy through a kinase-independent mechanism. The image shows the cardiac hypertrophy that develops in mice lacking PI3Kγ. [Image: Maradumane Mohan and Elizabeth Martelli/Lerner Research Institute, Cleveland Clinic Foundation]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882