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Cover Figure

ONLINE COVER This week features a Research Resource that describes a systems biology approach to understanding the signals from the mitochondria to the nucleus that occur when mitochondrial function is compromised. The image shows an artist's rendition of mitochondria. [Image: Chris Bickel, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882