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Cover Figure

ONLINE COVER This week features a Research Article with an accompanying Perspective that highlights how the calcium-sensing protein STIM regulates endothelial barrier function. The image shows an artist's rendition of a blood vessel. [Image: Yana Hammond, Science Signaling]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882