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ONLINE COVER This week continues a two-issue series focused on cancer. In this issue, a Perspective highlights the need to integrate both proteomic and signaling pathway data with genomic data to effectively develop cancer therapies. A Protocol describes how to use cBioPortal, an online resource for exploring genomic and proteomic data generated by large-scale cancer sequencing and characterization efforts. The image shows an artist's impression of integrating genomic data with signaling pathways to understand cancer. [Image: Chris Bickel, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882