F

FACS:

stands for fluorescence-activated cell sorting

FADD:

stands for Fas-associated protein with death domain; an adaptor protein that recruits caspases to death receptors; Connections Map Component -- Fas-associated protein with death domain

FAF:

stands for Fas-associated factor; a protein that interacts with the death domain-containing receptor Fas; Connections Map Component -- Fas-associated protein factor-1

FAK:

stands for focal adhesion kinase; a cytosolic nonreceptor tyrosine kinase; Connections Map Component -- Focal adhesion kinase

FAP:

stands for Fas-associated phosphatase; a protein tyrosine phosphatase; Connections Map Component -- Fas-associated phosphatase-1

Fas:

a death domain-containing member of the tumor necrosis family (TNF) receptor superfamily; Connections Map Component -- Fas

FasL:

stands for Fas ligand; a protein that activates the death domain-containing receptor Fas; Connections Map Component -- Fas ligand

Fbls:

a subfamily of F-box proteins with leucine-rich-repeats; these proteins specify substrates for SCF E3 ubiquitin ligases

Fbws:

a subfamily of F-box proteins that have WD40 domains; these proteins serve to specify the substrate for the SCF E3 ligase complexes

FGF:

stands for fibroblast growth factor; a family of protein ligands that activate fibroblast growth factor receptors, which can result in differentiation, proliferation, or morphogenesis; Connections Map Component -- Fibroblast growth factor

FIST:

stands for Fas-interacting serine-threonine kinase; also known as homeodomain-interacting protein kinase (HIPK3); Connections Map Component -- Fas-interacting serine/threonine kinase

FKBP:

stands for FK506-binding protein; an immunophlin, note that FK506 is an immunosuppressant drug

FKHRL1:

stands for Forkhead-related transcription factor 1; also known as FOXO3a , a member of the winged helix or Forkhead box (FOX) family of transcription factors; Connections Map Component -- Forkhead related transcription factor

FLICE:

stands for FADD-like interleukin-1β converting enzyme; also known as caspase-8, Mach5, or MACH; Connections Map Component -- Cysteine caspase-8

FLIP:

stands for FLICE-like inhibitory protein; an inhibitor of caspase-8 activation; Connections Map Components -- FLICE inhibitory protein short splice form | FLICE inhibitory protein long splice form

FOXO:

a subfamily of transcriptional regulators of the larger Forkhead (FOX) family, members of this subfamily include FOXO1 (also called FKHR), FOXO3a (also called FKHRL1), and FOXO4 (also called AFX); Connections Map Component -- Forkhead related transcription factor

FRET:

stands for fluorescence resonance energy transfer

FRP:

stands for Frizzled-related protein; a secreted protein that regulates Wnt signaling; Connections Map Component -- Frizzled-related protein

FYB:

stands for Fyn binding protein; also known as adaptor adhesion- and degranulation-promoting adaptor protein (ADAP) or Slp-76-associated protein of 130 kilodaltons (SLAP-130); a molecular scaffold

FYVE:

stands for Fab1p, YOTB, Vac1p, EEA1 domain; a 70-residue zinc finger named after the first four proteins known to possess it, mediates binding to phosphatidylinositol 3-phosphate [PI(3)P]

Fzo1:

stands for fuzzy onion; member of the dynamin family of large GTPases that is implicated in regulating mitochondrial morphology